The International Tinnitus Journal

Analyzing Hemodynamic Impacts of Two-Lung Versus One-Lung Ventilation in Thoracotomy Patients: Insights from Pleth Variability Index and Ultrasonic Cardiac Output Monitoring in a Comparative Study

Author(s): Babak Eslami, Jalil Makarem, Seyed Mohammad Mireskandari, Negar Eftekhar, Nima Nazari, Alireza Montaseri, Maryam Parnian, Manouchehr Nasrollahzadeh Saravi, Kaveh Hedayati Emami, Shahram Samadi*

Background: This research investigates the hemodynamic impacts of alternating between Two-Lung Ventilation (TLV) and One-Lung Ventilation (OLV) in thoracotomy patients, utilizing Pleth Variability Index (PVI) and Ultrasonic Cardiac Output Monitors (USCOM). Material and Methods: The design of this study is a pre-and-post intervention. The study was conducted at the Imam Khomeini Hospital Complex, a medical institution. The participants were 50 patients scheduled for elective thoracotomy requiring OLV. This study monitored transitions between TLV and OLV, assessing changes in various hemodynamic parameters such as heart rate, blood pressure, stroke volume variation, cardiac output, and PVI. Results: Outcomes were measured in terms of systolic and diastolic blood pressure, mean arterial pressure, stroke volume variation, cardiac output, and PVI during transitions. The study found no statistically significant changes in these parameters, indicating hemodynamic stability throughout the transitions. The study found no statistically significant changes in these parameters, indicating hemodynamic stability throughout the transitions. Conclusions: Hemodynamic stability in thoracotomy patients is not significantly affected by the transition between TLV and OLV, as indicated by PVI and USCOM measurements. These findings support the potential for safe management of ventilation strategies during thoracic surgeries.

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